Thalassemia major is the most severe form of the disease and can result in failure to grow, fatigue, facial bone deformities and jaundice. If you have questions or would like guidance, talk with a member of your health care team. Treatment depends on the type and severity of thalassemia. Beta thalassemia trait is also known as beta thalassemia minor. Thalassemia Major: The defect is in both globin chains; therefore, these people cannot produce required number of normal HbA hemoglobin. People with thalassemia intermedia (not as severe as major, but not as mild as trait) may need blood transfusions sometimes, such as when they have an infection or an illness. Wash your hands frequently and avoid sick people. Stem cell transplant. Your doctor also may recommend you take a folic acid supplement to help your body make new red blood cells. Two of the major ones are filtering the blood and monitoring the blood for certain infections. You'll also need an annual flu shot, as well as vaccines to prevent meningitis, pneumonia and hepatitis B. The mutation confers immunity to malaria, which is more prevalent near the coastline (hence the name). If one parent has beta thalassemia trait and the other parent has normal hemoglobin A, there is a 50 percent (1 in 2) chance with each pregnancy of having a child with beta thalassemia … Some people with thalassemia who don't have regular transfusions can also develop excess iron. Thalassemia is not contagious like HIV, but a woman can transfer Thalassemia to her child during her pregnancy. No treatment is necessary for thalassemia minor. … People with thalassemia minor or trait usually do not need blood transfusions because they either do not have anemia or have only a mild anemia. Thrombotic events include pulmonary embolism, arterial occlusion, portal thrombosis, and deep vein thrombosis. The low hemoglobin and fewer red blood cells of thalassemia may cause anemia, leaving you fatigued.If you have mild thalassemia, you may not need treatment. … When you have thalassemia, the spleen can get very big as it tries to make blood cells. What are the possible Complications of Beta Thalassemia Minor? Treatment might include: Blood transfusions. Every time a person gets a blood transfusion, their risk for a problem called “alloimmunization” goes up. To prevent iron overload, people with thalassemia may need chelation therapy, which is when doctors give a medicine – either a pill or a shot under the skin – to remove excess iron before it builds up in the organs. To help rid your body of the extra iron, you might need to take an oral medication, such as deferasirox (Exjade, Jadenu) or deferiprone (Ferriprox). The anemia does not affect your daily activities and you can usually manage without any treatment. Advertising revenue supports our not-for-profit mission. Another drug, deferoxamine (Desferal), is given by needle. This is especially important if you've had your spleen removed. There are no known complications associated with Beta Thalassemia Minor. Join the Public Health Webinar Series on Blood Disorders, Centers for Disease Control and Prevention. Alpha thalassemia is an inherited condition and requires both parents to be carriers. Many times people with thalassemia are prescribed a supplemental B vitamin, known as folic acid, to help treat … How is Beta Thalassemia Minor Treated? Don't hesitate to ask for help. Since your body has fewer red blood cells when you have thalassemia, you may have symptoms of a low blood count, or anemia. Treatment for moderate to severe forms of thalassemia … Eating a balanced diet that contains plenty of nutritious foods can help you feel better and boost your energy. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Compatible means that the donor has the same types of proteins, called human leukocyte antigens (HLA), on the surface of their cells as the person who will be receiving the transplant. One way to treat anemia is to provide the body with more red blood cells to carry oxygen. Northern California Comprehensive Thalassemia … But if you have a more severe form of the disorder, you may need regular blood transfusions. What's the most likely cause of my child's symptoms? Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Thalassemias are hereditary disorders characterized by defective … The destination website 's Privacy Policy linked below suspects your child has thalassemia, a cell! 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